Mrd in oncohaematology. Minimal cancer. Immune therapy of mrd.

08.50 Welcome address. Prof George Janossy, Prof Klaus Pantel, Prof Jean-Francois Rossi,

Prof Lydia Campos, Prof Bruno Brando & Dr Catherine Alix-Panabiиres

09.10 Who should be Involved in harmonizing MRD detection on solid tumours in PB and BM.Andy Rawstron,Leeds, United Kingdom

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09.50 MRD IN ONCOHAEMATOLOGY

Chairman: Prof Lydia Campos

09.50 Prof Lydia Campos, Saint-Etienne, France. State of the art in acute myeloid leukemia minimal residual disease assessment.

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10.10 Prof Christian Thiede, Dresden, Germany. NGS for upfront characterization and assessment of treatment response in AML and MDS.

10.30 Prof Gerrit Jan Schuurhuis, Amsterdam, The Netherlands. Minimal residual disease in AML and the role of leukemia stem cells herein.

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10.50 Coffee break

11.20 French myeloid database: relevant tool for anticipation the most frequent recurrent genetic abnormalitie and to improve the acute myeloid leukaemia diagnostic. Dr Carmen Aanei, Saint-Etienne, France

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11.40 MINIMAL CANCER

Chairmen:Prof Klaus Pantel & Dr Catherine Alix-Panabiиres

11.40 Circulating and disseminated tumor cells: biology and clinical significance.Prof Klaus Pantel, Hamburg, Germany

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12.10 Methods of CTC/DTC viability and function assessment. Dr Catherine Alix-Panabiиres, Montpellier, France

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12.40 Molecular characterization of single tumor cells by NGS. Anna Babayan, Hamburg, Germany

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12.50 Comparative analysis of multicolor flow cytometry and immunohistochemistry for the detection of disseminated tumour cells. Eszter Szбnthу, Debrecen, Hungary

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13.00 Selected poster presentations

13.00 Selection of DNA aptamers to human Interleukin-6 (hIL6). Vera A. Spiridonova, Moscow, Russia

13.05 Influence of c-MYC hyperexpression and RAS genes mutations on the disease prognosis and therapy response in multiple myeloma patients. M. V. Nareyko, E. Y. Demidova, A. M. Sergeeva,V. L. Surin & L. P. Mendeleeva, Moscow, Russia

13.10 Lunch

14.20 New data on DTC detection and monitoring by flow cytometry. Olga Beznos, Moscow, Russia

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14.50 Flow Cytometry for the identification of rare cells. Sara de Biasi, Modena, Italy

15.20 IMMUNE THERAPY OF MRD

Chairmen: Prof Jean-Francois Rossi, Katherina Psarra & Prof Bruno Brando

15.20 Myeloid suppressor cells in hematological malignancies. Katherina Psarra, Athens, Greece

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15.50 Myeloma and immune system: dangerous cross-roads. Prof Bruno Brando, Legnano, Italy

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16.20 Coffee break

16.50 Prof Jean-Francois Rossi, Montpellier, France. New frontiers in immunopathology: from dysimmune diseases to lymphoid malignancies.

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17.20 Targets for immune therapy of minimal residual cancer. Dr Alisa Petkevich, Moscow, Russia

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17.30 Mechanisms of chronic myelogenous leukemia cell death induced by a new inhibitor of Bcr-Abl tyrosine kinase. Dr Ekaterina Kolotova, Moscow, Russia

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17.40 Cancer tissue microenvironment biomarker profiling assay. Alex Chenchik, Cellecta

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Evening with Budapest Operetta