XI International Conference "Haematopoiesis Immunology"

"Bone marrow in cancer patients"

Mercure Budapest Buda, Hungary

June 6, 2014
09.00 Welcome addresses from conference organizers
Professor Klaus Pantel, MD, Ph.D, University Medical Centre, Hamburg-Eppendorf, Hamburg, Germany
Catherine Alix-Panabières, Ph.D, University Medical Center, Montpellier, UM1, Montpellier, France
Professor George Janossy, Academician of Hungarian Academy of Sciences, UCL, London, United Kingdom

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09.20 Plenary lecture: “Major role of bone marrow in tumor cell dormancy, distant metastasis formation and patient’s death”
Lecturer: Professor Serge A. Tjulandin, MD, Ph.D, DSc., Deputy Director of Cancer Research Center, Moscow, Russia
Moderator: Professor George Janossy, Academician of Hungarian Academy of Sciences, London, United Kingdom

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09.50 Immunohistological study of bone marrow in cancer patients
Chairman: Professor András Matolcsy, Head Dept. of Pathology, Budapest, Hungary

09.50 Malignancy in bone marrow: cellular interactions, Professor George Janossy
10.00 Classic immunohistology of trephine biopsies in malignancy: a bridge to the future,
Professor Giovanni Pizzolo, Verona, Italy

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10.30 Role of Bone marrow in study of MRD in haematopoietic tumors and DTC in cancer,
Professor Andy Rawstron., Ph.D., Consultant .Clinical Scientist, Leeds, United Kingdom

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11.00 Stromal bone marrow microenvironment in cancer development, Mauro Krampera, Verona, Italy

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11.30 Coffee break

12.00 Disseminated Tumor cell Biology
Chairman: Professor Serge A. Tjulandin, MD, Ph.D., Russia

12.00 DTC (Disseminated Tumor Cell) research: state-of-the-art & perspectives,
Professor Klaus Pantel, MD, Ph.D, Hamburg, Germany

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12.30 Challenges in DTC detection and viability assessment, Catherine Alix-Panabières, PhD, Montpellier, France

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13.00 Interactions of Macrophages and Cancer Stem Cells, Vera Donnenberg, PhD, Pittsburgh, USA

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13.30 Lunch break

14.30 Normal and metastatic bone marrow
Chairmen: Professor Klaus Pantel, MD, Ph.D, Hamburg, Germany and Catherine Alix-Panabières, Ph.D, Montpellier, France

14.30 Cancer Stem Cells: Cell Type or Cell State? Professor Albert Donnenberg, , PhD, Pittsburgh, USA

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15.00 Multicolor Flow Cytometric Analysis of Normal Bone Marrow, Professor Bruno Brando, MD, Milano, Italy

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15.30 Coffee break

16.00 Selected oral presentations
Moderator: Professor Suleyman Dincer, President of Turkish Haematology association, Turkey

16.00 Antigen expression heterogenicity used for mrd monitoring in b-lymphoblastic leukosis,
Valeriya Konashenkova, Ukraine

16.07 The monitoring minimal residual disease and maintanence therapy after autologous stem cells
transplantation in patients with multiple myeloma, Oleg Rukavitsyn, Russia

16.14 Stromal activation of bone marrow in infiltrative, lymphoid neoplasias, Judit Bedekovics, Hungary

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16.21 Detection of Disseminated Tumor Cells (DTC) in Patients with NSCLC and Esophageal Cancer,
Mikhail Kiselevskiy, Russia

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16.28 CD138+ and CD138- multiple myeloma cells demonstrate different embrane expression of
interleukin-6 receptor (CD126) and vascular endothelial growth factor receptor 3 (VEGFR3),
Maria Kostjukova, Russia

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16.35 Detection of bone marrow DTC in breast cancer using Flow cytometry, Oksana Bogomolova, Russia

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16.42 Detection of disseminated neuroblastoma cells in bone marrow using multicolor flow cytometry,
Alexander Popov, Russia

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16.49 New possibilities of disseminated breast cancer cell detection in bone marrow by acoustic
flow cytometry (Attune), Olga Beznos, Russia

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16.56 Pattern of bone marrow metastasis in solid tumours-A retrospective analysis at a Regional Cancer
Centre In Kashmir, Shiekh Aejaz Aziz, India

17.03 End of the conferences

19.00 Evening in Budapest Operetta

June 7, 2014
09.00 Bone marrow immunology
Chairman:
Professor Zaira G. Kadagidze, MD, Ph.D, DSc, Russia

09.00 Bone marrow myeloid-derived myeloid suppressor cells, Susanna Mandruzzato, PhD, Padova, Italy

09.30 Bone marrow plasma cells and its subsets. Methodological aspects of study, Bruno Paiva, MD, PhD, Salamanca, Spain

10.00 Peculiarities of bone marrow lymphocyte subpopulations in children with sarcomas,
Professor Nikolai N. Tupitsyn, MD, PhD, Russia

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10.20 Non-haemopoietic tumour cell detection by flow cytometry. Case presentations,
Zsuzsanna Hevessy, Associate Professor, Dept. Laboratory Medicine, University of Debrecen, Hungary

10.40 FISH (fluorescence in-situ hybridisation) on enriched bone marrow plasma cells,
Anikó Újfalusi, Assistant Professor, Dept. Laboratory Medicine, University of Debrecen, Hungary

11.00 Discussion

11.30 Coffee break

12.00 Haematologists and oncologists - Special lecture
Chairmen: Professor János Kappelmayer, MD, PhD, Debrecen, Hungary
12.00 Normal bone marrow hemopoiesis and its regulation
Lecturer: Professor Elena B. Vladimirsky, Israel

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12.30 Concluding remarks, Professor Janos Kappelmayer, MD, PhD, Debrecen, Hungary

12.45 Firm representatives: New technologies of bone marrow study
Attune NxT acoustic focusing cytometer, Björn Biedermann (Life Sciences)

13.30 Lunch break

14.30 Round Table: High technology methods of BM DTC detection: practical recommendations

16.00 End of the congress

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